You have probably heard a lot about the use of Ultrasound to help serums and anti-aging products to penetrate into the skin.
One such product is the Opal by Clarisonic.  It comes with a poly-peptide serum that is known to help fight the signs of aging.  

Opal states that:
Now there’s a Sonic Method for accelerating the reduction of fine lines and wrinkles far beyond the capabilities of topical treatments alone. The Opal Infuser boosts absorption of our anti-aging sea serum by driving the powerful antioxidants and hydrating marine extracts, deeper into the skin for younger-looking eyes faster.

However, after attending the Annual Aesthetics Convention (I was an Aesthetic Nurse), I learned of something even more effective.

A newer method now available is something called Electroportation
Electroportation uses modulated pulses of low current to create transient aqueous pores in the skin.  This application of an electrical pulse momentarily disrupts the cell membrane, allowing the entry of product.  When the pulse ceases, the membrane returns to its original structure, leaving product that has been penetrated into the interior of the cell.  The effect of the electroportation lasts for a few seconds, therefore, allowing the introduction of product. This dramatically increases skin permeability. In other words, it opens the pore that allows a deeper penetration of product into the skin  
This process also stimulates your skin to enable muscle toning, draining of liquids from intercellular space, and the production of new collagen and elastin.

In Summary: 

1.Ultrasonic:Ultrasonic is import nutrition by one million per second Vibration wave into the skin (slight shocks have no obvious feeling when used on the skin, usually USES the drop of water on the probe test whether at work or not) which is the most common and traditional leading instruments.
2. Electroporation: Compared with ultrasonic beauty instrument, electroporation import more products infiltrate into deep skin to improve via skin dermis; Compared with Ion,electroporation products leading penetration is 10-27 time than the Ion leading.

*****Ask your dermatologist about this before you try it out on yourself.  It may not be suitable for you, and there may be adverse side-effects.